Formulary Decisions

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Guselkumab
Tremfya
Routinely available
SMC (SMC2848)
13/05/2026

Indication

Treatment of adult patients with moderately to severely active ulcerative colitis (UC) who have had an inadequate response, lost response, or were intolerant to either conventional therapy, a biologic treatment, or a Janus kinase (JAK) inhibitor.

Treatment of adult patients with moderately to severely active ulcerative colitis (UC) who have had an inadequate response, lost response, or were intolerant to either conventional therapy, a biologic treatment, or a Janus kinase (JAK) inhibitor.

Therapeutic Area

Gastro-intestinal system

Status Description

Routinely available in line with national guidance

Formulation

Solution for injection in pre-filled pen and concentrate for solution for infusion

Comments

Link to Advice

SMC2848

Advice Published

10/11/2025

SMC Submission Type

Abbreviated

SMC Status

Accepted