Formulary Decisions

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Oxycodone
Oxycodone
Routinely available
SMC (648/10)
13/12/2023

Indication

Treatment of moderate to severe pain in patients with cancer. SMC restriction: patients who have difficulty in tolerating morphine or diamorphine therapy and who require a high dose of oxycodone delivered via syringe pump which necessitates the daily preparation of an additional syringe pump if oxyc...

Treatment of moderate to severe pain in patients with cancer. SMC restriction: patients who have difficulty in tolerating morphine or diamorphine therapy and who require a high dose of oxycodone delivered via syringe pump which necessitates the daily preparation of an additional syringe pump if oxycodone 10mg/mL is used.

Therapeutic Area

Central nervous system

Status Description

Routinely available in line with local or regional guidance

Formulation

50mg/ml solution for injection or infusion

Comments

Further restricted to use in a secondary care, hospice or community setting. This strength should be initiated by or under the supervision of a palliative care consultant. Care should be taken to minimise any risk of administration error with the introduction of this strength, refer to local board procedures for the safe supply. Noted intermittent supply constraints with diamorphine and price changes since original SMC advice. When diamorphine is available, oxycodone may be considered as an alternative option to diamorphine taking into consideration acquisition cost.

Link to Advice

648/10

Advice Published

08/11/2010

SMC Submission Type

Full

SMC Status

Restricted