Formulary Decisions

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Fentanyl
Instanyl
Not routinely available
SMC (750/11)
29/03/2023

Indication

For the management of breakthrough pain in adults already receiving maintenance opioid therapy for chronic cancer pain. Breakthrough pain is a transitory exacerbation of pain that occurs on a background of otherwise controlled persistent pain. SMC restriction: to patients who are unsuitable for othe...

For the management of breakthrough pain in adults already receiving maintenance opioid therapy for chronic cancer pain. Breakthrough pain is a transitory exacerbation of pain that occurs on a background of otherwise controlled persistent pain. SMC restriction: to patients who are unsuitable for other short-acting oral opioids (e.g. oral morphine) as an alternative to other buccal and sublingual fentanyl preparations. It should be noted that the doses of fentanyl nasal spray are significantly lower than doses of fentanyl given by other routes of administration for this indication.

Therapeutic Area

Central nervous system

Status Description

Not routinely available as local clinical experts do not wish to add the medicine to the formulary at this time or there is a local preference for alternative medicines

Formulation

50, 100, 200 microgram single dose nasal spray

Comments

-

Link to Advice

750/11

Advice Published

16/01/2012

SMC Submission Type

Abbreviated

SMC Status

Restricted