Formulary Decisions

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Tocilizumab
Tocilizumab
Routinely available
NICE (TA373 (SMC 930/13))
28/05/2025

Indication

Tocilizumab in combination with methotrexate is indicated for the treatment of juvenile idiopathic polyarthritis (rheumatoid factor positive or negative and extended oligoarthritis) in patients 2 years of age and older, who have responded inadequately to previous therapy with methotrexate. Tocilizum...

Tocilizumab in combination with methotrexate is indicated for the treatment of juvenile idiopathic polyarthritis (rheumatoid factor positive or negative and extended oligoarthritis) in patients 2 years of age and older, who have responded inadequately to previous therapy with methotrexate. Tocilizumab can be given as monotherapy in case of intolerance to methotrexate or where continued treatment with methotrexate is inappropriate.

Therapeutic Area

Musculoskeletal and joint diseases

Status Description

Routinely available in line with national guidance

Formulation

20mg/mL concentrate for infusion

Comments

NICE MTA advice: SMC advice 930/13 is superseded by NICE TA373. Refer to the treatment pathway or local guidelines for preferred formulation.

Link to Advice

TA373 (SMC 930/13)

Advice Published

16/12/2015