Formulary Decisions

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Insulin degludec + Liraglutide
Xultophy
Routinely available
SMC (1088/15)
29/03/2023

Indication

Treatment of adults with type 2 diabetes mellitus to improve glycaemic control in combination with oral glucose-lowering medicinal products when these alone or combined with a GLP-1 receptor agonist or with basal insulin do not provide adequate glycaemic control. SMC restriction: for use in patients...

Treatment of adults with type 2 diabetes mellitus to improve glycaemic control in combination with oral glucose-lowering medicinal products when these alone or combined with a GLP-1 receptor agonist or with basal insulin do not provide adequate glycaemic control. SMC restriction: for use in patients who are uncontrolled on basal insulin analogues (glycosylated haemoglobin [HbA1c] >7.5% [59mmol/mol]) and for whom a GLP-1 receptor agonist is appropriate as an add-on intensification therapy to basal insulin to obtain glucose control.

Therapeutic Area

Endocrine system

Status Description

Routinely available in line with national guidance

Formulation

100 units/ml / 3.6mg/ml solution for injection pre-filled pen

Comments

-

Link to Advice

1088/15

Advice Published

12/10/2015

SMC Submission Type

Full

SMC Status

Restricted