Formulary Decisions

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Tofacitinib
Xeljanz
Routinely available
SMC (1298/18)
22/05/2019

Indication

In combination with methotrexate for the treatment of moderate to severe active rheumatoid arthritis in adult patients who have responded inadequately to, or who are intolerant to one or more disease-modifying anti-rheumatic drugs (DMARDs). Tofacitinib can be given as monotherapy in case of intolera...

In combination with methotrexate for the treatment of moderate to severe active rheumatoid arthritis in adult patients who have responded inadequately to, or who are intolerant to one or more disease-modifying anti-rheumatic drugs (DMARDs). Tofacitinib can be given as monotherapy in case of intolerance to methotrexate or when treatment with methotrexate is inappropriate.

Therapeutic Area

Musculoskeletal and joint diseases

Status Description

Routinely available in line with national guidance

Formulation

5mg film-coated tablets

Comments

May 2019 - Routinely available in line with national guidance. Included on the Additional List, for Specialist Use only.

Link to Advice

1298/18

Advice Published

12/02/2018

SMC Submission Type

Full

SMC Status

Restricted