Formulary Decisions

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Guselkumab
Tremfya
Routinely available
SMC (SMC2360)
24/11/2021

Indication

Alone or in combination with methotrexate (MTX) for the treatment of active psoriatic arthritis in adult patients who have had an inadequate response or who have been intolerant to a prior disease-modifying antirheumatic drug (DMARD) therapy. SMC restriction: (i) patients whose disease has not respo...

Alone or in combination with methotrexate (MTX) for the treatment of active psoriatic arthritis in adult patients who have had an inadequate response or who have been intolerant to a prior disease-modifying antirheumatic drug (DMARD) therapy. SMC restriction: (i) patients whose disease has not responded adequately or who have been intolerant to two previous conventional disease-modifying antirheumatic drug (DMARD) therapies but have not received biologic DMARD therapy (biologic-naïve population); (ii) patients whose disease has not responded adequately to conventional DMARDs and one or more tumour necrosis factor (TNF) inhibitors (biologic-experienced population); and (iii) patients in whom TNF inhibitors are contraindicated or not tolerated.

Therapeutic Area

Musculoskeletal and joint diseases

Status Description

Routinely available in line with national guidance

Formulation

100mg solution for injection in pre-filled pen or syringe

Comments

November 2021 - Routinely available in line with national guidance. Included on the ERF for Specialist use only.

Link to Advice

SMC2360

Advice Published

09/08/2021

SMC Submission Type

Full

SMC Status

Restricted