Formulary Decisions

Indication

For the treatment of moderate to severe atopic dermatitis in adults and adolescents 12 years and older who are candidates for systemic therapy. SMC restriction: patients who have had an inadequate response to at least one conventional systemic immunosuppressant such as ciclosporin, or in whom such t...

For the treatment of moderate to severe atopic dermatitis in adults and adolescents 12 years and older who are candidates for systemic therapy. SMC restriction: patients who have had an inadequate response to at least one conventional systemic immunosuppressant such as ciclosporin, or in whom such treatment is considered unsuitable. In patients with moderate to severe atopic dermatitis eligible for systemic therapy, upadacitinib was associated with significantly greater improvements in the signs and symptoms of atopic dermatitis in adults and adolescent patients in three placebo-controlled phase III studies and in adult patients in one phase III comparative study with a monoclonal antibody.