Superficial basal cell carcinoma

Right Decision Service: Dermatology - Basal Cell Carcinoma

Treatment of superficial basal cell carcinoma
Imiquimod
Aldara 5% cream 250mg sachets

Apply cream for 6 weeks, 5 times per week (example: Monday to Friday) prior to normal sleeping hours, and leave on the skin for approximately 8 hours.

Fluorouracil
Fluorouracil 5% cream

See BNF for dose.

Prescribing Notes:

  • For more information, see Right Decision Service: Dermatology - Basal Cell Carcinoma.
  • Imiquimod cream 5% may be prescribed by dermatologists for the topical treatment of small superficial basal cell carcinoma in adults in whom standard treatment with surgery or cryotherapy is contraindicated.

History Notes

13/08/2025

Efudix (Fluorouracil) 5% cream debranded to Fluorouracil 5% cream, ERWG August 2025.

15/12/2021

East Region Formulary content agreed.