Reversal agents for cardiovascular medications
Reversal of unfractionated or low-molecular weight heparin overdosage
Protamine reverses the effects of unfractionated heparin but only partially reverses those of LMWH.
Protamine
Protamine sulfate 50mg/5ml solution for injection ampoules
History Notes
27/05/2026
Regional formulary chapter launched.
Reversal of direct oral anticoagulants (DOACs)
Reversal of apixaban or rivaroxaban. Also used for reversal of edoxaban (off-label use).
Andexanet alfa
Andexanet alfa 200mg powder for solution for infusion vials
Reversal of dabigatran.
Idarucizumab
Idarucizumab 2.5g/50ml solution for infusion vials
History Notes
27/05/2026
Regional formulary chapter launched.
Reversal of anticoagulation with warfarin or phenindione
Phytomenadione
Phytomenadione 10mg/1ml solution for injection ampoules
Phytomenadione 2mg/0.2ml solution for injection ampoules
History Notes
27/05/2026
Regional formulary chapter launched.
Reversal of life-threatening digoxin overdosage
Digoxin specific antibody
DigiFab 40mg powder for solution for infusion vials
History Notes
27/05/2026
Regional formulary chapter launched.